الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 105 |  |  |
| | | from | 105 | | |
Abstract
Breast cancer is considered one of the most frequent malignancies in women taking into consideration one-quarter of all malignancies diagnosed in women and could be a heterogeneous illness on the molecular level. This cancer is developed in breast tissues, including lobules and ducts. The worldwide deaths in women related to cancers represent a worldwide burden. Globally, Breast cancer incidence has been steadily increasing over the last few decades. Breast cancer was assessed to be 30% of recently analyzed cancer cases and about 15% of cancer-related deaths in women.
Breast cancer can be categorized as non-invasive or invasive. The surrogate intrinsic subtypes depend on key proteins histological and immunohistochemical examination: progesterone receptor (PR), estrogen receptor (ER), the proliferation marker Ki67, as well as human epidermal growth factor receptor 2 (HER2)