الفهرس 
Fabrication of a bioactive composite scaffold for drug delivery
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Abstract
The objective of this study was to fabricate of a bioactive composite scaffold for drug delivery aiming that the innovated tissue engineering scaffold be bifunctional. That innovated biocomposite scaffold should offer both good bioactivity to enhance cell adhesion, differentiation and proliferation as well as antimicrobial activity as a local drug delivery system to prevent bone infections and osteomyelitis at the surgical site of scaffold implantation. The bioactive composite scaffolds was fabricated from the chitosan polymer (which offered a biocompatible and biodegradable polycationic matrix) and the 46S6 bioactive glass (which provided bioactivity, improved the compressive strength and hindered the rapid ex vivo biodegradation of the prepared scaffold in order to enhance bone regeneration in stress bearing areas) and finally the GS drug as local antibiotic (which is prophylactic against the surgery accompanied sepsis