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العنوان
Azaenamines as building blocks for synthesis of heterocyclic compounds /
الناشر
Amr Mohamed Abdelmoniem Hassan ,
المؤلف
Amr Mohamed Abdelmoniem Hassan
هيئة الاعداد
باحث / Amr Mohamed Abdelmoniem Hassan
مشرف / Said Ahmed Soliman Ghozlan
مشرف / Ismail Abdelshafy Abdelhamid
مشرف / Holger Butenscho?n
تاريخ النشر
2014
عدد الصفحات
122 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
Organic Chemistry
تاريخ الإجازة
5/4/2015
مكان الإجازة
جامعة القاهرة - كلية العلوم - Organic Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 318

Abstract

The original work of this thesis is divided to three main original parts. In the first part, the reactivity of pyruvaldehyde phenylhydrazone derivatives was studied towards various (pyrazolylmethylene)malononitriles to synthesize 1,4-dihydropyridazine compounds bearing pyrazolyl groups and their condensed derivatives. Also, the reaction of the pyruvaldehyde phenylhydrazones with arylacrylamide derivatives was achieved to prepare new 1,4- dihydropyridazine compounds having carboxamide groups and their subsequent cyclizations to pyrimido[4,5-c]pyridazine derivatives that could also be synthesized from the reaction of pyruvaldehyde phenylhydrazone compounds with N-carbamoyl-2-cyano-3-phenylacrylamides in a single step