الفهرس 
Comparison between Pivka-II and interleukin-8 as early diagnostic markers for hepatocellular carcinoma
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Abstract
Hepatocellular carcinoma (HCC) is one of the most aggressive cancers worldwide. In Egypt, the disease is detected in an advanced stage at which no treatment may be effective including surgery. Among Egyptians, viral hepatitis is the most common risk factor for HCC. Early detection of the disease is thus an important goal allowing the patient to be treated before the enlargement of the tumor or its metastasis to distant organs. Serum tumor markers may be useful in predicting the tumor at early stages. The current work aimed to determine the level of prothrombin induced by vitamin K absence-II (PIVKA-II) and Interleukin {u2013} 8 (IL-8 ) in sera of patients suffering from HCC & cirrhosis and comparing which one is more sensitive and specific for early diagnosis of HCC. The current study was carried out on 120 individuals within three groups; Normal control, Cirrhosis and HCC groups. Complete examination was carried out for each individual to confirm diagnosis