الفهرس 
Formulation and Preclinical Evaluation of Certain Prepared Radiopharmaceuticals
ContentsOnly 14 pages are availabe for public view
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Abstract
Nuclear medicine field is directed to design and synthesize radiolabeled agents for diagnosis and therapy. The differences of the pathological and physiological processes between the tumor cells and the normal ones allow the differentiation ability between both of them. The in-vivo functional imaging techniques can help in diagnosing and staging tumors, optimizing drug scheduling, and predicting response to a therapeutic modality, which would be benefit for both patient and oncologist. In this manner, this method allows diagnosis in the initial stages, which plays a very critical managing role in the tumor treatment planning. By tumor growth, the disruption of the balance between oxygen supply and consumption inside the tumor cells create the hypoxic domain. Approximately half or more of locally advanced solid tumors may stimulate hypoxic tissue areas that are heterogeneously distributed within the tumor mass. A number of invasive methods have been developed for the measurement of hypoxia, but none of these is in routine clinical use because of their invasive nature, inconvenience, and inability to acquire repeated measures.