الفهرس | Only 14 pages are availabe for public view |
Abstract This study was carried out to investigate the possible therapeutic effect of camel milk on induced hepatocarcinogenesis in rats and comparably with other antitumor agent either natural (turmeric extract) or chemical (Cisplatin). This study was carried out to investigate the possible therapeutic effect of camel milk on induced hepatocarcinogenesis in rats and comparably with other antitumor agent either natural (turmeric extract) or chemical (Cisplatin). Induction of hepatocarcinogenesis was intitiated by diethylnitrosamine (DENA) and promoted by phenobarbitone. Body weight was recorded weekly. Whole blood, serum and liver and kidney Samples were collected. Relative liver and kidney weight, Biochemical analysis, hematology, lipid peroxidation and superoxide dismutase (SOD) activity in liver tissue were carried out. Histopathological studies of liver and kidney in addition to immunohistochemical staining of placental glutathione-s-transferase (P- GST) in liver were performed and the results were analysed using image analysis |