الفهرس | Only 14 pages are availabe for public view |
Abstract COVID-19 is an infectious disease caused by a newly discovered coronavirus. It is a pandemic spreading through all the world. Pregnant patients infected with COVID-19 appear to present similar to the general population, with fever and cough being the most reported symptoms in studies. Risk factors for death and severe disease include obesity, diabetes, and maternal age > 40 years. Women in their third trimester have the highest risk for critical illness, ICU admission, and need for mechanical ventilation. The clinical presentation of COVID-19 varies from asymptomatic to severe pneumonia with acute respiratory distress syndrome (ARDS) and multiple organ failure, often resulting in death. Most patients with COVID-19 develop severe acute respiratory illness accompanied by fever, cough, and shortness of breath. Progression to pneumonia is swift usually within the first week and at least one third of patients also present with gastrointestinal symptoms. COVID-19 progresses much more rapidly to respiratory failure and has a higher case fatality rate than SARS. The immune function of pregnant patients is relatively suppressed during pregnancy. At the same time, physiological changes during pregnancy will also expose pregnant patients to a higher risk, which will lead to more adverse outcomes. Limited information is available on the consequences of previous coronavirus outbreaks-severe acute respiratory syndrome coronavirus 1 (SARS-CoV-1) and Middle East respiratory syndrome coronavirus (MERS-CoV) on pregnancy. Despite the large number of pregnant women with the coronavirus disease 2019 (COVID-19), there is not enough analytical study to compare maternal and fetal consequences of COVID-19 infected with non-infected pregnancies. |