الفهرس 
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Abstract
Human and animal studies have shown that some drugs and
chemical agents have potential hepatotoxic effects. The hepatotoxic effect
of drugs and some chemical agents like MSG as flavor enhancer is
reported to be associated with the generation of reactive oxygen species
(ROS) and lipid peroxidation in the liver. This mechanism has led to
continuous evaluation of the hepato protective effect of antioxidants like
vitamin C in humans and animals.
This study included 36 adult male albino rats, which were divided
into six experimental groups. Liver function tests, oxidative stress and
anti-oxidant status were estimated. Moreover, histopathological
investigations of liver tissues were examined before and after treatment.
There are significant changes in liver function tests, oxidative
stress and antioxidant parameters were noted after treatment with vitamin
C. Moreover, the photomicrograph of liver tissue section show significant
improvement in-group treated with vitamin C after MSG administration.