الفهرس | Only 14 pages are availabe for public view |
Abstract More than 500,000 new patients are diagnosed every year with hepatocellular carcinoma (HCC) worldwide. Clusterin (apolipoprotein J) is a multifunctional glycoprotein exists in almost all mammalian tissue and most human body fluid. Recently, few studies have been done to evaluate serum clusterin role as a biomarker for diagnosis viral related hepatocellular carcinoma. The aim of this study is to evaluate the potential usefulness of clusterin as a new biomarker for diagnosis virus C-related hepatocellular carcinoma. Methods: Twenty-nine patients with HCC, twenty-nine patients with liver cirrhosis and thirty healthy controls were enrolled in the study. Estimation of serum clusterin was done by enzyme linked immunosorbent assay (ELISA). |