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العنوان
Intrathecal Nalbuphine versus
Fentanyl as Adjuvants to Hyperbaric
Bupivacaine in Hip Arthroplasty /
المؤلف
Mahmoud,Ziad Hashim Abdel Karim
هيئة الاعداد
باحث / Ziad Hashim Abdel Karim Mahmoud
مشرف / Mohammed Saeed Abdul-Aziz
مشرف / Hanna Mohamed AbdAllah Elgendy
مشرف / Hany Magdy Fahim
تاريخ النشر
2023
عدد الصفحات
105.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/8/2023
مكان الإجازة
جامعة عين شمس - كلية الطب - Anesthesiology
الفهرس
Only 14 pages are availabe for public view

from 116

from 116

Abstract

Background: Hip surgeries are one of the most cost-effective and consistently successful surgeries performed in orthopedics. Hip surgeries provide reliable outcomes for patients suffering from end-stage degenerative hip osteoarthritis (OA), specifically pain relief, functional restoration, and overall improved quality of life. Subarachnoid block is the preferred anesthesia for hip surgeries, being simple to perform and economical with rapid onset.
Objective: To compare intrathecal fentanyl in patients undergoing hip arthroplasty with nalbuphine as intrathecal adjuvant to 0.5% hyperbaric bupivacaine. The primary endpoint was the postoperative analgesia as assessed by VAS. The secondary outcomes were the onset and duration of sensory and motor blockade, hemodynamic changes, and incidence of side effects (bradycardia/ hypotension/ pruritus/ shivering/ respiratory depression/sedation).
Patients and Methods: This prospective double-blinded randomized clinical trial was conducted at Ain Shams University Hospitals from February 2022 until February 2023.
Results: As regard analgesic efficacy, there was increase pain in the two groups over the periods, but the most increase was in the fentanyl compared with nalbuphine group. There was a statistically significant difference between groups according to VAS score after 2:3 to 3:3 hours, while the rest times have insignificant difference. Sixteen patients received rescue analgesia with Fentanyl within 6h postoperatively, whereas six patients received with Naluphine which was found to be highly significant.
Conclusion: from our study we can conclude that there was increase pain in the two groups over the periods, but the most increase was in the fentanyl compared with nalbuphine group. There was a statistically significant difference between groups according to VAS score after 2:3 to 3:3 hours, while the rest times have insignificant difference. Sixteen patients received rescue analgesia with Fentanyl within 6h postoperatively, whereas six patients received with Naluphine which was found to be highly significant.