الفهرس 
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Abstract
Benign migratory glossitis or Geographic Tongue one of the most common tongue diseases as approximately one in 30 adults has geographic tongue. It occurs with symptoms like pain, burning sensation, discomfort, dysgeusia, sensitivity to hot, spicy and sour food, increased salivation, worry of the patient about probable malignancy or precancerous lesion. Since the primary etiology of GT is still mysterious, a definitive cure does not exist till now, and the present treatments are trying to relieve the symptoms.
Zinc is an essential trace element with a key role in several basic cellular functions in humans with a main role in wound healing, providing a healthy epithelium, in addition to reconstruction of filiform papillae which seem promising in management of BMG.
The objective of the present study was to evaluate the effectiveness of zinc supplementation in management of patients with symptomatic benign migratory glossitis.
The present study entailed 48 patients diagnosed with symptomatic benign migratory glossitis. Patients were divided equally into two groups; group A (study group) included 24 patients treated with zinc supplements combined with diet rich in zinc for one month. group B (control group) included 24 patients treated with only diet rich in zinc for one month.
Clinical parameters including the size of red atrophic areas (atrophic area length AAL, atrophic area width AAW), and VAS pain score. Both parameters were recorded at baseline, after one month of treatment and after one month later without treatment. Moreover, salivary samples were collected for biochemical analysis (measuring zinc levels) at baseline and after one month of treatment.
Results showed difference between groups as higher mean values of AAL and AAW were recorded in control group in comparison to study group after one month of treatment, that proved more improvement in study group than control group after one month of treatment. As for the second parameter which was VAS pain score, it was revealed that enhancement in symptoms of BMG in study group was significantly higher than control group after one month of treatment.
Regarding the biochemical analysis, significant higher values of salivary zinc levels were recorded after one month of treatment in study group (treated with zinc supplements combined with diet rich in zinc), in comparison to control group (treated with only diet rich in zinc).
Finally, results proved the role of salivary zinc deficiency in the development of BMG, considering the positive effect of zinc supplements administration on improving the atrophic areas, filiform papillae, and symptoms in patients with benign migratory glossitis.