الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
COVID 19 outbreak has emerged in China and has transferred virally to the whole world leading to SARS CoV2.
COVID 19 causes endothelitis and vasculitis mainly in the vessels of the lung, intestine heart, brain and kidney; this is due to a viral infection directly. As, the edema of endothelial cells, congestion and thrombosis may result in ischemia, reperfusion insult, causing dysfunction of multiple organ.
SARS CoV2 binds through ACE2 receptors to host cells which are found in many organs, like the lungs, heart, vessels, retina and aqueous humor. This can damage the retina and choroid by cytopathic effect directly via the ACE2 receptor or by an indirect inflammatory response. Also activation of the hyper coagulable condition by this cytokine pro inflammatory response resulting in a coagulation cascade.
The choroidal tissue has the highest blood supply in the whole body that may show changes in various systemic diseases, and may indicate vascular pathological processes related to them.
Evaluation of anatomy of choroid with in vivo images using EDI OCT is a noninvasive, inexpensive, reproducible method of imaging which provide us with high resolution images
Recently, CT and CVI especially are considered as main structural inflammatory markers. So, We wanted to investigate if COVID 19 may affect CT and CVI as an indicator of systemic inflammation caused by the disease.
Then, across sectional study was performed to evaluate the changes in CVI and CT in COVID patients early post recovery (15-30 days after recovery) and late after 6 months of recovery. And comparing the results with healthy age matched control subjects using EDI OCT and imageJ.
We found that CT was increased and CVI was decreased in COVID patients early after recovery. The changes were reversible, as it returned to normal later after 6 months.