الفهرس 
REVIEW OF LITERATUREOnly 14 pages are availabe for public view
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Abstract
Cancer is the major cause of mortality worldwide as tumor cells have developed
resistance to most chemotherapeutic agents. Thymoquinone has anticancer properties, wever, the main problems associated with thymoquinone, are low solubility and stability, us, limiting its usage in medicinal applications. In our study, we tried to develop a hymoquinone-loaded liposome and study its anti-cancer effect in-vitro and in-vivo. We gan with the preparation of thymoquinone-loaded liposome using the thin-film method ollowed by liposomal characterization including particle size, zeta potential, morphology nd entrapment efficiency %. The in-vitro anti-tumor activity was tested on the HepG2 cell ine. Colony forming, wound healing, cellular uptake, and apoptotic effects of the formulation ere assessed.