الفهرس 
ANESTHETIC CONSIDERATION FOR LAPAROSCOPIC SURGERYOnly 14 pages are availabe for public view
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Abstract
ABSTRACT
Background: Laparoscopic surgeries are becoming popular due to several postoperative benefits allowing quicker recovery, less tissue damage, avoiding big surgical incision, shorter hospital stay with consequent reduction in health care cost.
Objective: To evaluate the efficacy of dexmedetomidine infusion in patients undergoing laparoscopic abdominal surgeries as an opiates reducing agent according to the intraoperative hemodynamics and postoperative opioid analgesic rescue.
Patients and Methods: We conducted a double blinded 2-arms parallel controlled trial in Ain-Shams University Hospitals. 60 patients were randomly divided into two groups (30 patients in each group). Patients of group (A) received dexmedetomidine infusion 0.7 mcg/kg as a loading dose, followed by 0.2 mcg/kg/h as a maintenance intraoperative dose. Postoperative dose was 0.1 mcg/kg/h for 24 hours. Patients of group (B) received an infusion of saline without dexmedetomidine, using similar infusion sets, rate intraoperatively and postoperatively.
Results: The results of the study demonstrated that dexmedetomidine infusion was associated with significantly less intraoperative and postoperative SBP, DBP, MAP, and heart rate, pain scores, and pethidine consumption. Dexmedetomidine, however, was associated with significantly higher postoperative sedation scores with no ill-effect on ventilation.
Conclusion: In patients undergoing laparoscopic abdominal surgeries, dexmedetomidine infusion was associated with significantly less intraoperative and postoperative SBP, DBP, MAP, and heart rate, pain scores, and pethidine consumption. Dexmedetomidine, however, was associated with significantly higher postoperative sedation scores with no ill-effect on ventilation. Further studies are recommended to validate the role of perioperative dexmedetomidine in laparoscopic abdominal surgeries.