الفهرس | Only 14 pages are availabe for public view |
Abstract At the end of 2019, a novel coronavirus (ie, SARS-CoV-2) was identified as the cause of a cluster of pneumonia cases in Wuhan, a city in the Hubei Province of China. By 2020, it led to a pandemic that has spread throughout most countries of the world. SARS-CoV-2 disease (COVID-19) primarily manifests as a lung infection with symptoms ranging from those of a mild upper respiratory infection to severe pneumonia, acute respiratory distress syndrome, and death. Although respiratory failure and hypoxaemia are the main manifestations of COVID-19, kidney involvement is also common. Kidney disease among patients with COVID-19 can manifest as AKI, hematuria, or proteinuria, and portends a higher risk of mortality. It remains unclear if AKI is largely due to hemodynamic changes and cytokine release or if the virus also leads to direct cytotoxicity. |