الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Advances in the diagnosis and treatment of MR have generated scholarly discussions on the need to reevaluate the timing of surgery for these individuals in order to improve their clinical outcome. The currently accepted referral criteria for traditional MV operation or MV percutaneous intervention has some limitations in terms of identifying patients who are developing subtle structural and functional LV and LA impairment, with MV repair/replacement occasionally being the resulting referral when irreversible myocardial damage has already occurred. Two-dimensional Speckle tracking echocardiography, one of the most popular and easily available advanced echocardiographic techniques, is accomplished by a rapid, semi-automated analysis of mostly obtained 2D echocardiographic images.
It has been utilized for the assessment of patients with rheumatic MR because it may be used to detect mild myocardial fiber damage early on and provides early signals for heart dysfunction caused by slight myocardial impairment.It has shown to be a reliable early diagnostic and prognostic indicator in a number of clinical situations.
In our research, 200 patients with rheumatic MR were involved: 100 with severe rheumatic MR who did not qualify for surgery and 100 with mild rheumatic MR who acted as a control group.
Transthoracic 2D echocardiography, GLS, and a three-month follow-up were carried out on all patients who were enrolled to check for the development of any new symptoms.
In our research, we found that GLS is more sensitive than LVEF in spotting early LV systolic dysfunction impairment in rheumatoid MR. GLS may be useful for managing patients over the whole range of MR patients, stratifying prognosis, and even figuring out when interventional treatments should be performed.