الفهرس 
Immune ThrombocytopeniaOnly 14 pages are availabe for public view
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Abstract
Background:
Primary Immune thrombocytopenia (ITP) is an autoimmune disease characterized by both platelet destruction and impaired platelet production.
Vitamin D regulates the growth and differentiation of various cells of the immune system through acting on vitamin D receptors (VDRs) expressed on these immune cells.
Studies have demonstrated the role of VDR polymorphisms in the development of various autoimmune diseases.
Aim of the Work To find the correlation between vitamin D receptor gene polymorphism and outcome in primary and resistant immune thrombocytopenic patients under Eltrombopag therapy.
Study design: Exploratory comparative cross-sectional study.
▪ Study Setting:
The study will be conducted at Ain Shams University Hospitals, Hematology department.
▪ Study Period: 2022-2023.
▪ Study Population:
Thirty ITP patients reclassified into 15 primary ITP patients in remission and 15 Resistant ITP patients.
Inclusion Criteria:
The patients should be diagnosed and investigated for primary ITP and resistant ITP according to Society of Hematology guidelines (ASH)