الفهرس 
Esophageal strictureOnly 14 pages are availabe for public view
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Abstract
Purpose: The purpose of this research was to determine if topical MMC treatment following dilatation in children who had resistant post-corrosive esophageal strictures (CES) was effective. •Materials and methods This interventional randomised prospective controlled study was performed on 40 children with resistant post-corrosive esophageal strictures. Participants had been allocated into 2 groups at random utilizing the closed envelope approach; group I: participants for whom repeating oesophageal dilatation was conducted without MMC application. group II: treated with repeating oesophageal dilation and topical application of MMC following dilatation repeated four times within 2-week intervals. Patients from group II were further subdivided into two equal groups: group A: with short-stricture (less than 3cm) in length as identified with radiological assessments and verified with endoscope. group B: with long stricture (>3cm) in length as identified with radiological assessments and verified with endoscope. •Results: Dysphagia had statistically significant improvement in 60% of the long and short stricture groups following mitomycin administration contrasted to just 25% of the control group. Endoscopic dilatation sessions following mitomycin had been statistically more common in the control group, accounting for 15 sessions, as contrasted with 6 sessions in the groups with both long and short strictures. •Conclusions The topical administration of MMC was linked with substantial improvements in the manifestations of dysphagia and a reduction in the frequency of endoscopic dilatation sessions among children with post-corrosive esophageal stricture. •Keywords Topical,Application ,Mitomycin C, Resistant ,Post Corrosive Esophageal Stricture.