الفهرس | Only 14 pages are availabe for public view |
Abstract Background: Crohn’s disease is a chronic inflammatory bowel disease that can affect any part of the gut. Endoscopy is the gold standard for diagnosis, but it only assesses mucosal lesions. Magnetic resonance enterography (MRE) can assess disease presence and activity, but it has limitations such as motion sensitivity, long scan time, and high cost. Bowel ultrasound (BUS) has been introduced as a non-invasive, practical, and low-cost technique to assess disease activity and complications. Results: 25 patients with 38 Crohn’s disease affected segments were evaluated by bowel ultrasound (BUS) and MRI enterography (MRE), where BUS and MRE showed equivalent diagnostic performance for disease detection and localization (97.4%, 100%), for sensitivity and specificity of both modalities. BUS showed high sensitivity and specificity for perimural fluid presence (89.5%, 94.4%), and mural stratification loss (100%, 100%) compared to MRE, while for assessment of mural vascularity, BUS showed high sensitivity, and specificity for high grade vascularity (100%, 83.3%), but low sensitivity and high specificity for low and moderate vascularity (0% - 62.5%, 81.8%) compared to MRE. Complications including fistulae and abscessed were all correctly identified in BUS compared to MRE resulting in 100% for sensitivity and specificity. Conclusions: BUS showed comparable results to MRE for identification, localization, assessment of findings related to disease activity and complications in cases of Crohn’s disease rendering it a viable alternative to MRE |