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العنوان
Study of clinico pathological aspect and managment of cancer cervix cases in
shatby hospital/
المؤلف
Abd El-Latif, Amira Mohamed .
هيئة الاعداد
مشرف / اميرة محمد عبد اللطيف
مشرف / محمد السيد مليس
مشرف / حسام حسن السكري
مشرف / مرفت على محمد السرسى
الموضوع
Obstetrics . Gynecology.
تاريخ النشر
2023.
عدد الصفحات
45 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب
تاريخ الإجازة
19/9/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Obstetrics and Gynecology
الفهرس
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Abstract

Cervical cancer is a malignant tumour of the cervix that can be divided into two histological types, adenocarcinoma (AC) and squamous cell carcinoma (SCC). SCC is more common and has an occurrence rate of 70%. AC originates from glandular cells that line the cervical canal (the endocervix), whereas SCC originates from squamous cells lining the outer part of the cervix that opens to the ectocervix. The region in which the squamous and the thin, flat glandular cells are located is termed the transformation zone, and the majority of tumours originate from this zone.(1)
In Egypt, women aged 15 to 44 are most likely to get cervical cancer, which is the 10th most common cancer overall and the 13th major cause of cancer in women. In 2012, 866 new instances of cervical cancer were identified, and 373 people died as a result of cervical cancer in Egypt. According to reports, there were 2.3 incidences of cervical cancer among Egyptian women per 100,000 in 2012.(47)
This study was conducted toanalyze cervical cancer cases as regard, clinical aspect, age distribution, histopathology, stage at presentation, grade at presentation, primary modality of therapy and treatment to outline the magnitude of the problem in order to help in designing a program for prevention and build up a data base for future reporting of new cases.
In the present study, the mean age of cervical cancer cases was 47.72±12.375 years (24-78 years). Our study agreed with Yang et al., (2021) study which showed that the mean age of included patients with cervical cancer was 45 years. Overall, 54.161% of patients were aged <45 years, and 3.752% patients were aged ≥60 years.(48)
In line with our results Sharma et al. (2018) reported that the study population included participants from urban and rural areas of 11 different districts of Karnataka. Udupi district had the maximum number of cases (52.7%). Maximum numbers of cases (41%) were in the age group of 51–60 years old followed by 34% in 41–50 year age group (Fig.3). Age of the participants ranged from 35–78 years. Mean age of the study population was 53.2 years (±9.8). In case group, the age of cases ranged from 35–77 year with mean age of cases is 54.2 (±9.3). In control group the age of the participants ranged from 35–78 year. Mean age of the participants was 52.7 (±10).(49)In Gravdal et al., (2021) study, there has been an increase in cervical cancer incidence in women under the age of 30.(50)
However, our result was lower than reported in Park et al., (2018) study which revealed that the median age of cervical cancer patients was 53 years (interquartile range [IQR], 45 to 60 years).(51) Likewise, the mean age of the patients at the time of diagnosis was 56.9+13.0 and ranged from 31-90 years in Farahat et al., (2021) study.(52)
According to Tuncer et al., (2021) findings and those of previous studies, age plays an important role in the development of CIN (1). Thus, taking age in consideration is crucial in the diagnosis of CIN (1) on cancer screening. Women aged 25-29 as compared to those aged 20-24 are two times more likely to have CIN (1). CIN (1) lesions are 1.149 times more likely to develop with each one-year age progression.(54)
Carcinoma of the cervix is a common malignancy among women of developing countries.Young age