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العنوان
Ultrasound versus computed tomography in staging of ovarian cancer/
المؤلف
Hamed, Heba Ahmed Mohamed Mahmoud.
هيئة الاعداد
باحث / هبة أحمد محمد محمود حامد
مناقش / عمرو عبد العزيز السيد
مشرف / محمود حنفى مليس
مشرف / أحمد سامى العجوانى
الموضوع
Obstetrics. Gynecology.
تاريخ النشر
2023.
عدد الصفحات
55 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
9/10/2023
مكان الإجازة
جامعة الاسكندريه - كلية الطب - Obstetrics and Gynecology
الفهرس
Only 14 pages are availabe for public view

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from 69

Abstract

OC is the second most prevalent gynecologic malignancy and the sixth most frequent cancer among women diagnosed globally. Consequently, one of the most fatal tumours that strike women is OC.
The recommended course of treatment for advanced-stage OC is either (a) primary cytoreductive surgery, also known as ”debulking,” followed by platinum-based adjuvant chemotherapy, or (b) neoadjuvant platinum-based chemotherapy, if nonresectable disease is discovered during preoperative imaging.
The single most significant independent prognostic factor in advanced OC has been proven to be complete resection to no residual disease during initial or interval debulking surgery. Preoperative imaging provides crucial information on tumor resectability, but surgical inspection is the only method to know if full debulking is possible.
Preoperative disease evaluation must be seen as clinically relevant in order to ensure effective patient treatment, which includes sufficient counselling, referral to gynecologic oncology centers, scheduling the availability of multidisciplinary surgical teams, and adequate triaging. Different methods have been investigated for their potential to predict in advance whether each patient will have the best possible cytoreduction. The accuracy of preoperative blood CA125 levels has been found to vary from 50 to 78 percent based on analyses of CA125 levels, radiographic evaluation of tumour dissemination, and more recently, laparoscopically based ratings. The most used imaging method for pre-operative staging is CT, which has a reported accuracy of between 70% and 90%. But in recent years, US has drawn interest as a method for spotting OC’s intra-abdominal spread of the illness. TVAS according to Savelli et al., may find bowel and pelvic carcinomatosis.
Currently, US is regarded as the primary imaging method for differentiating between benign and malignant tumors. Its use for radiological staging of OC, however, has historically been seen as restricted. It may be quite helpful in making the initial diagnosis of gynecological malignancies, determining the extent of the tumor in the pelvis and abdominal cavity, assessing the effects of the therapy, and monitoring patients after treatment. Additionally, advanced tumors or metastatic lesions may be targeted for biopsy using US, making it possible to quickly and less invasively determine the tumor’s histology.
This research compares the diagnostic efficacy of CT and US for identifying pelvic and abdominal tumor spread in OC patients.
Women with clinical and radiological suspicion were the eligible candidates in this cross-sectional investigation, which included 124 patients.
In our study:
Regarding gravidity, 27 (21.8%) cases were nullipara, and 97(78.2%) cases were multipara.
Age ranged from 45-75 years with a mean value (±SD) of 56.10 ± 6.99years with median (IQR) of 55.0 (50.0 – 61.0) years.
BMI ranged from 17-50 kg/m2 with a mean value (±SD) of 31.95 ± 6. kg/m2 with median (IQR) of 31.0 (27.0 – 36.0) kg/m2.
Comorbidities were HTN in 20 (16.1%) cases, DM in 19 (15.3%) cases and thyroid disease in 6 (4.8%). 79 (63.7%) cases had no comorbidities.