الفهرس 
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Abstract
Epicardial adipose tissue (EAT) is a true visceral fat depot, confined under the visceral pericardium. The current literatures show that EAT is a metabolically active organ generating proatherogenic and proinflammatory cytokines. EAT volume continued to be a highly reliable indicator of coronary atherosclerosis. The relationship between EAT and the thrombus burden in STEMI patients is not well studied.
The aim of the study was to evaluate the relationship between the epicardial adipose tissue thickness, the coronary arteries thrombus burden and the early major adverse cardiovascular events in STEMI patients experiencing pPCI.
Patient clinical, laboratory, angiographic and echocardiographic data were described. Patients were observed to detect the occurrence of any major adverse cardiovascular events, either in the hospital or during a period of 30-day follow-up.
The results of our study showed that:
There was a higher prevalence of male patients in the study population with a higher percentage of male patients in the low thrombus burden group versus the high thrombus burden group with a statistically insignificant difference. The median age was nearly equal with a statistically insignificant difference between the two groups.
The median weight is higher in the high thrombus burden group with a statistically significant difference (p = 0.002). The median height among both groups is nearly equal with a statistically insignificant difference. The median body mass index is higher in the high thrombus burden group with statistically significant difference (p = 0.003). There is statically significant difference between both groups according to the prevalence of normal and abnormal waist circumference (p = 0.026). The median waist circumference is higher in the high thrombus burden group with a statistically significant difference (p = 0.001).
In our study, the prevalence of having cardiovascular risk factors (smoker, ex-smoker, drug addiction, DM and HTN) and the mean Wall motion score and Wall motion score index among both groups were nearly equal with statistically insignificant difference. The prevalence of having a positive family history for coronary artery disease among both groups is higher in the high thrombus burden group with a statistically insignificant difference.
The mean levels of high sensitivity troponin I and creatine kinase MB are measured higher in the low thrombus burden group with statistically significant differences (p = 0.025) and (p = 0.032).
Balloon predilation was statistically significant difference between the two groups (P = 0.006). Thrombus aspiration, balloon postdilation of the culprit vessel, GpIIb/IIIa inhibitors usage, and one stent only pPCI were insignificant differences between the two groups.
The mean epicardial adipose tissue thickness was statistically significant lower in the low thrombus burden group than in the high thrombus burden group.
The cut-off value of EAT to predict the grade 4 and 5 thrombus burden was 2.48 mm, that has 74.55% sensitivity and 72.0% specificity for prediction of the high thrombus burden (AUC: 0.75795% confidence intervals: 0.641–0.874; P<0.001).
The overall MACE at 30-day follow-up has a statistically insignificant difference between both groups.