الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Myopia is a relatively common ocular disorder with approximately 0.5% to 1% prevalence of high myopia in the population. In high myopic eyes, pathologic myopia, also known as ”myopic macular degeneration”, ”myopic maculopathy”, or ”degenerative myopia” can occur, which can lead to visual acuity decline. The advance in optical coherence tomography (OCT), and spectral-domain OCT (SD-OCT) in particular, helped identifying more subtle changes in the myopic macula and follow up scans also helped with detecting the minimal changes in macular area. Extensive studies were conducted to evaluate macular changes in eyes with high myopia while myopic macular changes after cataract surgery have not been widely investigated. The purpose of the present study was to evaluate and report postoperative macular changes in eyes with high myopia, as determined by SD-OCT. The current study was a prospective study carried out on 86 eyes of high myope patients attending to (Mansoura ophthalmic center) diagnosed with cataract requiring surgery. The following data was obtained for each study participant: * Demographic data. * History of previous intraocular surgery, neurologic, metabolic or systemic disease. * Full ophthalmologic examination: -Visual acuity assessment: best corrected visual acuity (BCVA) using Landlots’ broken ring chart. -Cycloplegic refraction. -Intraocular pressure using applanation tonometer. -Anterior segment slit lamp examination. * Intraocular lens (IOL) master 500 (Carl Zeiss Meditec, Jena, Germany) for the measurement of the AL. * OCT images were obtained with Spectralis SD-OCT (3D OCT-2000 series, Topcon, Japan) at baseline and at one week, 3 and 6 months after the operation. Follow-up scans were compared with previous images to detect subtle changes. All results of the current study were statistically analyzed. In the present study: •The mean age of the studied group was (mean ± SD= 55.79 ± 8.092 years). 47.7% of the patients were males and 52.3% were females. •51.2% of the studied group had right operative eye while 48.8% had left operative eye. The mean axial length was (Mean ± SD= 30.15± 1.77). •23.3% had cortical and nuclear cataract, 20.9% had mixed type of cataract and 19.8% had nuclear and PSC type. •The cyclopegic refraction was significantly higher in the preoperative than the postoperative after one week, three months and six months. •The BCVA was significantly higher in the preoperative than postoperative after one week, three months and six months. •There was non-significant difference between the preoperative and postoperative IOP after one week, three months or six months. •There were significant differences between the preoperative and postoperative fundus examination (macular edema) after three months and six months. •There was non-significant difference between the preoperative and postoperative PVD after one week, three months or six months. •The postoperative cystoid macular edema after six months was significantly higher than preoperative and postoperative after three months. •There was no statistically significant difference in the postoperative central macular thickness after 1 week, three months and six months. Conclusion : Cataract surgery has significant effect on the visual acuity of highly myopic eyes. The outcomes of the present study suggest that phacoemulsification has no clinically relevant detrimental impact on the incidence or evolution of macular pathologies in eyes with high myopia. Moreover, the incidence of CME in these eyes seems to be higher than that in normal eyes and needs further studying. Careful preoperative assessment, Intraoperative management and frequent follow up of patients with detailed fundus examination is recommended to detect the complications. Limitations : - Had limited ability to gain access to the appropriate type or geographic scope of participants. - Require a larger sample size to ensure that the sample is considered representative of a population and that the statistical result can be generalized to a larger population. - Lack of previous research studies on the topic. The problem of having limited access to these respondents.