الفهرس 
Aim of the work
Norepinephrine in spinal anesthesia induced hypotensionOnly 14 pages are availabe for public view
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Abstract
Hypotension following neuraxial blockade is due to sympathetic inhibition, which causes a significant decrease in the venous return due to dilatation of the resistance and capacitance vessels.
Norepinephrine has been recently described as a possible alternative to phenylephrine for maintaining BP during spinal anesthesia for CS.
This work aims to study the role of norepinephrine infusion in maintaining hemodynamic stability in patients undergoing CS as a primary outcome and monitoring infant wellness as a secondary outcome.
This study was conducted on 40 patients divided into two equal groups. group I received a norepinephrine infusion, and group II received no prophylactic vasopressor and a bolus of 5 μg norepinephrine whenever systolic BP decreased to <80% of the baseline value.
Blood pressure variation after the start of medication showed a significant decrease in group II than in group I after 10, 20, 30, 40, 50, and 60 minutes.
There was no significant difference in heart rate between group II and group I after 10, 20, 30, 40, 50, and 60 minutes. Also, there was no significant difference in fluid response (thoracic fluid content) between group II and group I after 10, 20, 30, 40, 50, and 60 minutes.
Regarding stroke volume variation and cardiac index, there was a significant decrease in group II compared with group I at 10, 20, 30, 40, 50, and 60 minutes.
The APGAR score showed no significant difference between the two groups.