الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Adjacent Segment Disease (ASD) is a significant complication that can develop after lumbar spine fusion surgery. ASD is characterized by degeneration of the spinal segments immediately adjacent to the site of previous spinal fusion, which is thought to be partly due to the altered biomechanics of the spine following fusion surgery. This loss of motion increases the range of motion and mechanical stress on non-fused segments adjacent to the fusion site, leading to accelerated wear and tear, resulting in degenerative changes that manifest as ASD.
The development of ASD has significant clinical implications, as new or recurrent symptoms can affect the patient’s quality of life and often necessitate further medical or surgical treatment, including possible extension of the fusion to adjacent levels. Understanding the factors contributing to the development of ASD and devising strategies for its prevention are areas of active research in spinal surgery.
The prevalence of ASD following lumbar fusion surgery has been extensively studied, but the reported rates vary widely owing to differences in study designs, patient populations, follow-up durations, and definitions of ASD. Symptomatic ASD, which is of greater clinical concern, has been reported to occur at a rate of approximately 5% to 30% following lumbar fusion surgery.