الفهرس 
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Abstract
Genital warts are the most common sexually transmitted diseases caused by certain types of HPV. Moreover, anogenital warts are a significant public health problem with global estimates of incidence of 160-289 cases per 100,000 person years.
There are many strategies for treatment of genital wart like ablative therapies, e.g., topical chemical cautery, cryotherapy, electrocautery, excision, bleomycin sulfate injection and laser vaporization, and also immunotherapy.
Podophyllin resin is one of the oldest nonsurgical treatments available. It is compounded as a 10%–25% suspension in tincture of benzoin. Topical 25% P peltatum resin extract could accomplish regression of condylomas. However, long term efficacy rates originally claimed have not been confirmed, recurrence rates being 33–55%.
On the other hand, immunotherapy relies on enhancement of the cell mediated immunity to the human papillomavirus (HPV) to induce clearance of all warts and have led to promising results in skin diseases such as molluscum contagiosum, melanoma.
DPCP, is a topical universal sensitizers and non-mutagenic in Ames test and it does not appear to have significant systemic absorption after topical application. Nevertheless, its effectiveness in treating genital warts was not conclusive.
Therefore, our study aimed to compare the clinical effectiveness of topical Diphenylcyclopropenone and topical Podophyllin in genital wart treatment.