الفهرس | Only 14 pages are availabe for public view |
Abstract White sesame (Sesamum indicum) and Thyme (Thymus vulgaris) are grains characterized by containing a large amount of minerals such as calcium , flavonoids and Antioxidant, which have been found to play an effective role in Osteoporosis. So that, this study sought to investigate the effect of white sesame and thyme against osteoporosis in rats induced by Glucocorticoid. Forty male albino rats (140-150g) were used and fed on a basic diet for with 7 days for adaptation. rats were divided into two main groups; group 1 (5rats) was negative and group 2 (35 rats) was divided into 6 treatment group and were injected Glucocorticoid for all periods of experimental (10 mg/kg per daily): group 1 and 2 were fed on white Sesame powder (2.5% and 5%). group 3 and 4 were fed on thyme powder (2.5% and 5%). group 5 and 6 were fed on white Sesame and thyme mix powder(2.5% and 5%). All serum and bones samples were analyzed for determination the following parameters: Serum and bone (Ca), (P), and (Mg) values and (OC) and (IL-6) levels and (PTH) and (DPD) level and (CRP) . The result indicated that eating white sesame and thyme or their mixture improve bone efficiency, increase Ca and Mg in serum and bones and increase OC and DPD in serum But decrease p in serum and bone and decrease il-6 and CRP in the rats compared to the positive control . The best result was a mixture of 5% of white sesame and thyme. AS conclusion, consequently, we must use a mixture of white sesame and thyme powder in our daily dishes. |