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Abstract he rate-limiting stage in achieving optimal concentration at the targeted absorption site is the drugs dissolution that taken orally. Additionally, a key element in influencing the drug’s bioavailability is the rate of dissolution. Pharmaceutical companies have recently focused on creating medical formulations that can be taken orally. Oral medication delivery is frequently hampered by issues including poor water solubility and dissolution rate. Additionally, about roughly sixty percent of the drugs resulted from synthesis and forty percent of drugs in the development exhibit poor solubility, hence have limited absorption and bioavailability. |