الفهرس 
Aim of the workيوجد فقط 14 صفحة متاحة للعرض العام
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المستخلص
Diabetic ketoacidosis (DKA) is a prevalent cause of Acute Kidney Injury (AKI). There has been an increase in the use of novel biomarkers in various clinical settings for the diagnosis of AKI.Neutrophil Gelatinase-Associated Lipocalin (NGAL) has not been extensively studied for its ability to predict chronic AKI in DKA patients,Aim and objectives;to evaluate common risk factors that usually correlated with development of AKI in DKA patients, and to compare the role of different biomarkers in early accurate detection of kidney injury, Subjects and methods: This was a prospective cohort study was conducted in Port-Said General Hospital ( El Salam ) at Internal medicine department on 60 patients who admitted to ICU between August 2021to April 2022 with DKA, divided into 2 groups: (group A): DKA patients with high level of NGAL test result on admission , (group B): DKA patients with normal level of NGAL test result on admission, Result;Therewas significant positive Correlation between NGAL and serum creatinine after 7 days and negative correlation between GFR after 7 days, urine output after 7 days in group A and in group B positive correlation with FBG after 7 days,Conclusion;A severe complication of DKA, AKI is influenced by age, Glu, SUA, and WBC levels, pH, serum Alb, coma, and previous CKD. AKI is frequent in DKA upon presentation.We discovered that uNGAL and serum creatinine showed a strong association, and that their rise correlated with the stage of AKI. As most AKI was treated with hydration, more extensive prospective trials are required to assess the usefulness of uNGAL in predicting chronic AKI.The morbidity and mortality linked to acute kidney damage should be greatly decreased by earlier identification and treatment.