الفهرس 
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Abstract
Background;VitaminDisindispensableforskeletaldevelopment&maturation. Numerous recent studies, on the other hand, have demonstratedthatvitaminDisalsocrucialforimmunity,&shortageinthisnutrientislinkedtoinfections.
Aims and objectives: to assess levels of 25-hydroοxy vitamin D in critically illkids& toinvestigate the associationof levelsof 25(OH)D withPRISM IIIscoresinkidswithcritical illness.
Subjectsandmethods;Thiscase-controlresearchwasperformedon30children with critical illness confined to the Intensive Care Unit of Pediatric ofEl-Salam Port-Said General Hospital. In addition to 30 healthy children as thecontrol group.
Result;WasnotedSerum25(OH)Dlevelwassignificantlydecreasedincritically ill children compared to control group (p=.007). There is a statisticallysignificantcorrelationamongstPRISMIIIandSerum25(OH)D(ng/ml)(p<.001). There is a statistically significant correlation amongst PRISM III &CV-SOFA (p=.019).
Conclusion; the findings of the current research demonstrated that was noted ahigh frequency of vitamin D shortage amongst critically sick children relative totheircompatiblehealthypeers. The correlation amongst PRISM III & serum 25(OH)D was negative, whilebetween PRISM III& Cv-SOFAwaspositive.