الفهرس 
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Abstract
This work aimed to study the role of 3-T MRI in the comprehensive evaluation of bladder cancer applying VI-RADS system. It was conducted prospectively on 80 patients with bladder cancer lesions based on clinical examination and previous imaging.
All the patients were subjected to thorough history taking and review of their clinical data and previous imaging. They underwent a MRI study on 3-T device having a full bladder in accordance to the VI-RADS standardized protocol.
Images were interpreted by two radiologists independently including the VI-RADS score, ADC values by volumetric and ROI methods and the usual imaging variables. The gold standard histopathological analysis was obtained by TURBT specimens for all patients, re-TURBT for 21 patients and subsequent radical cystectomy for 19 patients.
Inter-reader agreement on different VI-RADS score categories and ADC values was calculated. Statistical analysis of the relations between different MRI variables including the VI-RADS score and the state of muscle invasion as well as the tumor grade were studied. Logistic regression analysis was performed to evaluate the most important features predicting muscle invasion and high tumor grade. The diagnostic accuracies VI-RADS score categories, calculated ADC values as well as different combinations of features were determined by the ROC curve analysis.