الفهرس 
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Abstract
Functional bowel disorders (FBD) are highly prevalent disorders found worldwide. These disorders have the potential to affect all members of society, regardless of age, sex, race, creed, color, or socioeconomic status. Irritable bowel syndrome (IBS) occurs as recurrent abdominal pain that is related to defecation and associated with a change in frequency and/or form of stool in the absence of any other disease to cause these sorts of symptoms. It is one of the disorders of (FBD).
IBS is a common disease occurring at all geographical latitudes. The prevalence of IBS in the global population is estimated at 11%. The prevalence of IBS in women is about twice as high as in men. Half of patients report their first symptoms before the age of 35.
This study aimed to assess colonoscopic findings in patients fulfilling ROME IV criteria of irritable bowel syndrome with or without recently discovered alarming features.
This cross-sectional study was carried out on sixty consecutive patients who attended the Hepatology, Gastroenterology, and Infectious Diseases Department. Detailed history taking, clinical examinations, and laboratory investigations in the form of CBC were performed. All patients underwent full colonoscopy, and biopsy specimens were obtained for histopathological examination. Findings consistent with organic disease were defined, and patients were classified accordingly.
The participants were divided into two equal groups:
group A: 30 patients fulfilled Rome IV criteria of irritable bowel syndrome without alarming features.
group B: 30 patients fulfilled Rome IV criteria of irritable bowel syndrome with recently discovered alarming features.