الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 93 |  |  |
| | | from | 93 | | |
Abstract
The aim of this study was to assess the corneal endothelial cell density and morphology in high myopic eyes in different age groups; 18 - 35-year (group A), 35 - 55-year (group B), > 55-year (group C) and compared to healthy emmetropic eyes in the same age-group.
This was a case-control study, conducted at Outpatient Clinic, Ophthalmology department, Suez Canal University Hospital, Ismailia, Egypt for a period of six months from February 2021 to July 2021. A total of 168 eyes of 84 participants were enrolled, they were allocated into two groups: [group I (42 cases, 84 eyes): individuals with high myopic eyes, group II (42 cases, 84 eyes): individuals with healthy emmetropic eyes as a control group.
There was a decrease in ECD in older participants. It can be inferred from our finding that the ECD in high myopic eye was decreased significantly, p < 0.05 and this decrease was age dependent.
There were statistically significant differences in the mean endothelial cell density (ECD) and hexagonal appearance of the cell (P < 0.05) between high myopic and emmetropic eyes. While there were no statistically significant differences in coefficient of variation CoV %, (P > 0.05) among high myopic and emmetropic eyes.
Previous studies reported that factors that affect the corneal endothelial cell density and morphology are corneal disease, glaucoma, pseudo-exfoliation, history of trauma, Diabetes Mellitus, age, race, ocular surgeries (