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العنوان
Optic nerve head microvascular changes after phacoemulsification surgery /
المؤلف
Abdallah, Raouf Mamdouh Mohamed.
هيئة الاعداد
باحث / رؤوف ممدوح محمد عبدالله
مشرف / معتز الصاوي
مشرف / مروه علي ذكي جلال
الموضوع
Phacoemulsification. Cataract Surgery.
تاريخ النشر
2024.
عدد الصفحات
63 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
الناشر
تاريخ الإجازة
10/6/2024
مكان الإجازة
جامعة المنوفية - كلية الطب - طب وجراحة العيون
الفهرس
Only 14 pages are availabe for public view

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from 96

Abstract

Phacoemulsification is a cataract surgery technique that is frequently used and has very successful visual results. After cataract surgery, some changes in ocular hemodynamics and IOP have been reported in various studies. OCTA is a non-invasive and highly repeatable imaging technique that can show the peripapillary microvascular structure.
OCTA is a new, non-invasive imaging technique that uses motion contrast imaging to obtain high-resolution volumetric blood flow information and generate angiographic images in a matter of seconds. A split-spectrum amplitude-decorrelation angiography (SSADA) algorithm can be used to display local microcirculation. SSADA can measure both transverse and axial flow with the same sensitivity.
Regarding Sociodemographic data of the studied group our results showed that, the mean age was 59.4 ± 10.1 Std. The sex distribution in the studied groups observed that, 66.6% were female, while 33.3% were male. The difference, however, was non-statistically significant (p-value= 0.25).
Our study aimed to determine optic nerve head microvascular changes detected by optical coherence tomography angiography and intraocular pressure changes after uncomplicated phacoemulsification surgery.
We collected pre-and post-operative data from 60 eyes of patients with cataract who underwent OCTA imaging and IOP measurement pre-operatively and post operatively. Patients were selected from eye outpatient department at memorial institute of ophthalmologic research hospital, Egypt, and eye outpatient department at Menofia university hospitals.
Our findings observed that, there were a significant improvement of visual acuity following uneventful cataract surgery over 1-4 weeks follow up (p<0.0001). Also, a significant decline of IOP following uneventful cataract
Summary
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surgery was noted over 1-4 weeks follow up (p<0.0001).
In the current study, the mean OCT angio optic disc vasculature dynamic of the whole, inside, and the peripapillary region showed early non-significant decline, followed by regaining of pre-operative baseline after uneventful cataract surgery p-values were 0.11, 0.10 and 0.18 respectively.
The present study showed that, EPT has weak and non-significant correlations to changes in IOP and visual acuity (p-value 0.30, 0.20 respectively); as well as OCT Angio parameters (p-value 0.63, 0.72, 0.79 respectively). Although these correlations were non-significant.
Our results observed that, the strongest positive correlations were only found among OCTA optic disc parameters, coinciding with negative correlation with IOP. Week correlations were noted among visual acuity, EPT, and OCTA optic disc parameters, denoting that uneventful cataract surgery has minimal influence on the optic disc vasculature. significant improvement of visual acuity following uneventful cataract surgery over 1-4 weeks follow up, significant decline of IOP following uneventful cataract surgery over 1-4 weeks follow up, early non-significant decline, followed by regaining of pre-operative baseline after uneventful cataract surgery were detected in our study. Based on our finding we concluded that, Week correlations were noted among visual acuity, EPT, and OCTA optic disc parameters, denoting that uneventful cataract surgery has minimal influence on the optic disc vasculature. More reliable results can be obtained with a larger number of patients and longer postoperative follow-up.