الفهرس 
Introduction and Aim of the workOnly 14 pages are availabe for public view
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Abstract
Doxorubicin (DOX) is one of the frequently prescribed chemotherapies because of its high anticancer activity, but initiation of cardiotoxicity limits its medical usage. The possible ways that were proposed to clarify the DOX-induced injury include oxidative stress (OS), minerals dysregulation, modifications in cardiomyocytes structure and expressions of important genes, mitochondrial disorder, cardiomyocytes apoptosis, and endothelial cells and blood vessels toxicity.Usage of the chemicals that were developed to protect the heart is frequently associated with unwanted side effects, such as weight gain, hypertension, gastric ulcer, and insulin resistance. On the other hand, consumption of vegetables and fruits has been associated with abundant health benefits, as a result of their high nutritious content and therapeutic abilities. For instance; Zingiber officinale (Ginger) has an elongated history in herbal medicine to treat a diversity of disorders including vomiting, indigestion, pain, and cold-induced symptoms. In addition, it possesses anti-clotting, anti-inflammatory, analgesic, and anti-cancer activities. Moringa oleifera is the most broadly distributed species, mainly in Asian countries, and is recognized for numerous pharmacological properties. Leaves, flowers, roots, seeds, and immature pods of M. oleifera are believed to act as anti-pyretic, anti-tumor, anti-epileptic, anti-ulcer, anti-inflammatory, diuretic, anti-hypertensive, anti-diabetic, hepatoprotective, anti-fungal, and anti-bacterial activities; Persicaria maculosa (Polygonaceae), several types of Polygonaceae are rich sources of bioactive ingredients that contribute to a wider range of medicinal properties. The previous literature revealed some of its pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, anti-tumour, anti-ulcerogenic and antileukemic activities; and Citrus sinensis or orange (Rutaceae) is the world’s most common fruit. Orange peel is a decent source of polyphenols which may be used as potential antioxidants and used as food additives.