الفهرس 
Ventricular Septal DefectOnly 14 pages are availabe for public view
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Abstract
Background: Ventricular septal defect (VSD) is currently the most common congenital heart disease found in the pediatric population, representing 20% of isolated congenital heart diseases.
Aim and objectives: Assess the short and intermediate term outcomes of perimembranous or muscular transcatheter VSD closure on the ventricular performance using three-dimensional speckle tracking echocardiography (3D-STE) and hence LV reverse remodeling.
Patients and methods: This was a Prospective observational study conducted at 112 children (56 Pediatric population with congenital perimembranous subaortic VSD or muscular VSD who underwent transcatheter VSD device closure in the cardiology department of Ain Shams University Hospitals and 56 healthy pediatric population of the same age
Results: There was no significant difference between the control group and the study group preoperatively, 24hr, and six months postoperatively as regard end diastolic volume (EDV), end systolic volume (ESV), stroke volume (SV) but there was significant increase in EF (ejection fraction), global longitudinal strain (GLS), global radial strain (GRS) and global circumferential strain (GCS) between preoperative study group and 6 months postoperative study. There was no significant difference between control group and 6 months postoperative study as regards EF.
Conclusion: In the current study, there was a significant increase in GLS, GRS, GCS and EF after VSD transcatheter closure, which concludes the decrease in LV volume overload with the improvement of its contractility in intermediate outcomes. Transcatheter closure of VSDs is safe and effective.