الفهرس 
Diabetes mellitus and cardiovascular diseaseOnly 14 pages are availabe for public view
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Abstract
Abstract
Background: diabetes is one of the most important metabolic conditions responsible for left ventricular (LV) dysfunction including LV hypertrophy. Increased left ventricular mas (LVM) is a strong predictive factor of LV hypertrophy.
Study purpose, design, and methods: LVM is suggested to be useful in detection of LVH in diabetics , our study included 100 persons distributed in the 2 groups
1- group A (cases) : 50 patients with type 2 DM with normal blood pressure without antihypertensive medication .
2- group B (controls) : 50 normotensive non-diabetic patients as a control group.
LVM was measured by trans-thoracic echocardiography using Devereux Formula.
Results: LVM values were significantly higher in cases than controls (187.11 ± 60.83 vs. 119.15 ± 41.87, p<0.001). As well as, LVMI values were significantly higher in diabetic cases than controls (96.64 ± 29.84 vs. 63.17 ± 20.38, p<0.001), Proportion of abnormal LVMI was higher in diabetic cases than controls (56% vs. 6%, p<0.001), There was a statistically significant positive correlation between LVM and several study parameters including mainly disease duration (r=0.369, p=0.008), FBS (r=0.478, p<0.001), 2HPP (0.400, p=0.004), HA1C (%) (r=0.589, p=0.003), LVEDD (r=0.790, p<0.001), LVESD (r=0.388, p=0.005), SWT (r=0.897, p<0.001), PWT (r=0.808, p<0.001), and LA (r=0.322, p=0.022).
Conclusion: LVM is significantly higher in normotensive type 2 DM patients when compared to controls. LVM is a good marker of LVH among normotensive diabetics and is markedly correlated with DM control and duration.