الفهرس 
CHAPTER ONEOnly 14 pages are availabe for public view
 |  | from | 51 |  |  |
| | | from | 51 | | |
Abstract
Lung cancer is considered the most common cause of cancer-related deaths in males and females worldwide. The incidence and mortality of lung cancer may vary according to smoking status, gender, ethnicity, environmental exposures, and economic state. Obstructive sleep apnea (OSA) is characterized by recurrent episodes of upper airway partial or total collapse leading to hypopnea or apnea, respectively. The prevalence of OSA varies widely worldwide. Intermittent hypoxemia and sleep fragmentation play an important role in the inflammatory state in OSA and are responsible for many consequences as cardiovascular complications, diabetes mellitus and metabolic syndrome, psychological problems including depression, reduced quality of life and cognitive dysfunction. The association between OSA and lung cancer has been explored and several studies suggested that lung cancer increases the risk of OSA and that OSA enhance the occurrence of lung cancer.
The aim of this work was to assess the burden of obstructive sleep apnea hypopnea syndrome among patients newly diagnosed with lung cancer and assess the performance status of those patients.