الفهرس 
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Abstract
First of all, I am greatly indebted to gracious Allah for helping and me all over my life, the most merciful who granted my ability and willing to start and complete this work.
I like to make special thanks to my supervisor Prof. Dr. Mostafa Fayez Mohamed Hassan Professor of pharmacology, Faculty of Veterinary Medicine, Suez Canal University, who is my senior and often advised me, guided me to research methods and for his kindness, patience and cooperation to facilitate any obstacle.
Great thanks to Prof. Dr. Abdul - Fatah Mohamed Abdul - Fatah Professor and Head of pharmacology department, Faculty of Veterinary Medicine, Suez Canal University for his kindness, encouragement and support.
It is my pleasure to express my appreciation and thanks, gratitude to deal with my supervisor Prof. Dr. Waleed Fathi Khalil Professor of pharmacology, Faculty of Veterinary Medicine, Suez Canal University, who has cheerfully answered my queries, support, encouragement and for his patience and tolerate throughout the study and working.
It’s one of the best chances to express my appreciation and sincere gratitude to my supervisor Prof. Dr. Fatma Mohamed Ahmed Youssef Professor of Clinical pathology, in Animal Health Research Institute, Ismailia branch, for her great help in all steps of works, assisted me in myriad ways with the writing and practical works also, I have gained valuable experience in the work and her useful suggestions in all stages of this thesis.
I’d like to express my gratitude to Dr. Mohamed Helal Researcher in Animal Health Research Institute -Ismailia branch for his great helpful comments.
All thanks and appreciation to my sister En. Walae Ismail Mohamed for her great effort to finish this work.
I’m grateful to have her, and I’d like to thank her for outstanding support Dr. Rania Elsnosy in Animal Health Research Institute -Ismailia branch for her great exertion.