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العنوان
Synthesis and studies of some new heterocyclic compounds /
المؤلف
Hamama, Wafaa Salama Ali.
هيئة الاعداد
باحث / وفاء سلامه على حمامه
مشرف / أ. م. خليل
مشرف / ه. ه. زوروب
مناقش / ه. ه. زوروب
الموضوع
Heterocyclic compounds. Chemistry, Organic.
تاريخ النشر
1982.
عدد الصفحات
101 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
01/01/1982
مكان الإجازة
جامعة المنصورة - كلية العلوم - Department of Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 129

Abstract

The interesting pharmacological properties of quinoline derivatives led us to study the various changes in the structure of this compound, to synthesize some less toxic and more potent drugs. One of these variations is the introduction of heterocyclic moieties in the 3-position of the quinolone. (I) Reaction of 3-Acetyl-1,2,3.4-tetrahydro-2.4-dioxo-1-phenyl-quinoline (1) with Amines and Diamines: Treatment of 3-acetyl derivative (1) with the appropriate aromatic amines gave the corresponding anil derivatives (2a-g).