الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 186 |  |  |
| | | from | 186 | | |
Abstract
The large number of seriously injured patients now requiring treatment, the long term disability associated with skeletal injury, underline the socioeconomic importance of attempts to expedite healing. Among methods using hormone agents, growth hormone has been used clinically as an adjuvant in treatment of fractures. Human growth hormone is known to affect the metabolism of bone; it is necessary for the normal development and growth of bone. It also increases the formation and resorption of bone in the adult skeleton resulting a net increase in bone mass. Although most of authors described a benificial effect of growth hormone the healing of long bones in humans, especially in cases of delayed or non-union, there has been little overall uniformity about the experimental such treatment. The aim of this work was to study the secretory profiles of human hormone during various stages of fracture healing and to try to possible correlation between these changes and healing status. In the present study 24 prepubertal children (19 boys, 5 girls) with ranged from 6-11 years with recent, closed diaphyseal femoral fractures, of different levels, and of different patterns were studied. Any patient with associated head, chest or abdominal injury was excluded. Also we have excluded any patient with pathological, open, or multiple fractures as well medical diseases. The selected patients were subjected to clinical, radiological and assessments, closed reduction in thomas splint and post-reduction 7 mid-night blood samples were taken from each patient at 2nd