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Abstract The prevalence of HEV antibodies as a factor for hepatic impairment in children with ALL was the aim of this work. The materials of the present study include 25 children with ALL in complete remession and 10 healthy’ children as a control. The results of our work revealed : No significant difference, as regard number of blood transfusion, between cases positive for HCY and cases negative for HCY. Significant decrease in white blood cells and platlets in cases positive for HCY as compared to control. Significant decrease in haemoglobin, red blood cells and white blood cells in cases negative for HCY as compared to control. No significant difference as regard blood picture in cases positive for HCY versus cases negative for (HCY and HBY). Therefore the haematological differences may be attributed to the depressive effect of chemotherapy on bone Significant increase in AST,ACl, alkaline phosphatase and Significant decrease in Prothrombin activity, serum albumin in cases positive for HCY as compared to control group. Significant increase in AST,ACr and significant decrease in prothrombin activity, Serum albumin in cases negative for HCY as compared to control. Significant increase in AST, AIT and significant decrease in serum albumin in cases positive for HCY versus cases negative for Hey. Significant increase in AST, ALT and significant decrease in serum albumin. |