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العنوان
Influence of oral calcium channel blockers on the plasma level of insulin and cortisol in rats /
المؤلف
Abd El-Aziz, Mohamed Abd El-Ghany.
هيئة الاعداد
باحث / Mohamed Abd El Ghany Abd El-Aziz
مشرف / El-Hamy Mohamed Mounir El-Kholy
مشرف / Ali Mohamed Gaballah
مشرف / El-Sayed El-Khodary
الموضوع
Plasma level of insulin and cortisol - Oral calcium channel blockers.
تاريخ النشر
1989.
عدد الصفحات
216 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأدوية (الطبية)
تاريخ الإجازة
1/1/1989
مكان الإجازة
جامعة المنصورة - كلية الطب - DEPARTMENT OF PHARMACOLOGY
الفهرس
Only 14 pages are availabe for public view

from 190

from 190

Abstract

The present Work was cOnducted to study the effects of the CaH channel blockers verapamil and nifedipine on the serum glucose , insulin and cortisol levels in the non di abeti c and di abet i c rats , as We II as , any nossr b Ie interactions between these CaH channel blockers and the oral hYPoglycaemic glic]azide With regard to their effect on the serum glucose, insulin and cortisol levels 0 The data obtained in the stUdy could be summarized as fallows: 1- Verapamil in a Single oral daily dose Of 20 mg/kg for success i ve 15 days , prodUCed a high) Y s i gni fi can t increase of the mean serum glucose level in the non diabetic rats and inSignificant Changes in alloxan diabetic rats. The serum inSUlin level was reduced Significantly in both groups. Serum cortisol level was not Significantly altered in both.