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Abstract Approximately one in rune women living to the age of 70 years will develop breast cancer in her life time. The most common presentation is painless breast lump and is usually described by patients as thickening or uneasy different feeling. The high incidence of breast cancer, vague non specific early presentation, and the importance of early detection, necessitate the need for a non invasive modality to screen and accurately diagnose breast cancer. Several non invasive modalities have developed including physical examination, mammography, ultrasound and Doppler, CT, MRI and recently laser mammogrophy and nuclear medicine techniques. It is unquestionable that mammography is still to be considered the reference method for the study of breast masses; infact, its application in clinical practice has substantially reduced the mortality due to breast cancer. Nevertheless, situations such as dense breast tissue, the presence of a microcalcification, without a palpable mass, severe scarring after surgery with or without radiation therapy, detection of malignancy around silicon implants, and other selected problem cases like the detection of internal quadrant tumors represent a major challange in breast cancer management. In addition, the evaluation of local and regional lymph nodal involvement represent a very important problem .. |