الفهرس 
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Abstract
The inhalational anaesthetic, Isoflurane produces sympathatic activity mainly beta, increased heart rate, peripheral varodilatation and dose-dependent decrease in systemic arterial , pressure. The cerebral effect of isoflurane includes, decreased cerebral vascular resistance, vascular dilatation and dosedependent increase in cerebral blood flow, cerebral blood volume and intracranial tension. The resultant rise in ICP during an anaesthetic-induced· reduction in systemic blood pressure may critically reduce CPP and cause focal or generalized ischemia. Good reduction in intracranial tension can be achieved by diuretics as loop diuretic frusemide or osmolar diuretic as mannitol which still the most commonly used diuretic In neurosurgery. This study has been planned to evaluate the most suitable anaesthetic and diuretic regimen for patients subjected to Brain tumour resection. The associated changes in haemodynatnics: CVP, JBP parameters as well as the estimations of cerebral blood flow and cerebral Inetabolic rate of oxygen were used for this evaluation.