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Abstract This study was carried out at the period between May 1997 to ber 1999 in intensive care unit of Mansoura emergency hospital and cic medicine department, Mansoura university hospital. It included *ients,, with age range -from 20 to 50 years, (24 mates and 17 les),The aim of this work was to study the clinical and biological indices predict the development and outcome of patients with acute lung try It included two groups: Patients at risk for acute lung injury ( at risk group): It included 16 patients, (I I males and 5 females) with mean age of 33.3±10.5 years to identify the onset predictors. The risk factors for ALI in this group included; septic shock, aspiration pneurnonia,mhalational lung injury and ricar drowning patients. Patients with acute lung injury (ALI group) It included 25 patients (I 3 males and 12 females) with mean age of 33.8±9.04 years to identify the outcome predictors. The acute lung injury score by Murray 1988 was adopted as a strategy for selecting and categorizing those patients based on CXR, PaO2/FiO2, static compliance and PEEP. Patients with ALI score less than 2.5 were assumed as mild to moderate ALI, while those with ALI score 2.5 were categorized as severe ALI or ARDS. .riteria for eiclusion: Patients below 15 and above 60 years F. Patients with cardiogenic pulmonary oedema. 3. Patients with Uraemic pulmonary oedema. 4. Patients known with pre-existing pulmonary disorders. as, pulmonary . |