الفهرس | Only 14 pages are availabe for public view |
Abstract Pediatric cardiomyopathy is a serious disease. Our study was carried ron 27 children with DCM together with 10 normal healthy children of tched age and sex. Diagnosis of DCM was based on the presence of uced left ventricular ejection fraction secondary to diffuse wall motion ormality as determined by echocardiography. All cases and controls were subjected to the following: Full history and thorough clinical examination. jChest x-ray. Electrocardiographic examination. I)Echocardiographic examination: including M-mode, two-dimensional, and Doppler echocardiography. Determination of serum free carnitine levels. We divided our patients, depending on the severity of disease and if into 2 subgroups; group I with relatively better clinical situation and EF :::: 40% as (good responders), and group II with bad clinical situation land EF < 40% as (non-responders). Our results revealed the following: 2)There was no significant difference of age at presentation between responders and non-responders (P = 0.318) 3)A highly significant decrease in SBP in patients with DCM compared to control group (P = 0.003) with no significant difference (P = 0.368) between responders and non-responders 4)A highly significant increase of CT ratio in patients with DCM compared to control group (P<O.OOI) and also between responders and non-responders compared to controls with no statistically significance difference between responders and non-responders 5)Arrhythmias were detected in 11% of patients with DCM with no statistically significance difference between responders and non¬responders 6)Echocardiography revealed a highly depressed myocardial systolic function (EF & FS) (P<O.OOI) in patients with DCM compared to control group and also between responders and non-responders (P<O.OOI). |