الفهرس 
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Abstract
This study was conducted on forty patients of both sex suffering from severe head injury, to evaluate the effect of changing the tidal volume and the ventilatory rate on hemodynamics and blood gases during mechanical hyperventilation.
These patients were classified into two equal groups, A and B.
The two groups were hyperventilated for 24 hours. Group A received VT 12 ml/kg at a ventilatory rate 12/minute. Group B received VT 6 ml/kg at a ventilatory rate 24/minute.
The data used for assessment included heart rate, arterial blood pressure (systolic, diastolic, and mean), central venous pressure, peak airway pressure, pH, PaC02, HC03, Pa02 and O2 saturation.
The results of this study revealed that, there were no statistically significant differences between the two groups except an increase in peak airway pressure, mild decrease in central venous pressure, mild increase in pH, and mild decrease in PaC02 in group A than in group B.
These differences were mild and still in the normal ranges and without clinical significance. We concluded that decreasing the tidal volume with increasing the ventilatory rate could be used safely with less incidence of barotrauma and without significant side effects.