الفهرس 
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Abstract
Intracavernosal injection therapy (IC1) is an effective therapy for erectile dysfunction (ED). In addition to its use as a therapeutic modality, it may also be used in a diagnostic capacity, to differentiate between the various etiologies of ED, such as psychogenic, neurogenic, arteriogenic, or venogenic dysfunction. The aim of our study was to identify the cause underlying weak erections in patients with inadequate response to intracavernosal injection and to compare the results of different tests used for the diagnosis of ED. A total of 104 ED patients were evaluated at the Andrology Clinic at Mansoura University Hospital. All men underwent a standard ED evaluation that included general and sexual history, general and local genital exam, serum glucose, testosterone, and prolactin levels. . All patients then received a test dose of IC1 with Trimix (papaverine, phentolamine, PGEl). Patients then underwent evaluation with nocturnal penile tumescence (NPT) testing with the Rigiscan device, penile blood flow studies (PBF) using color duplex ultrasonography, and re-dosing pharmaco-cavernosometery (RFC) using CAVOMAT 7000. Results of these adjunct!ve tests were compared to the outcome of the ”Trimix” 1C I using different statistical methods. Analysis of our results showed that: • 30 patients responded with a rigid erection to ICI (group 1) while 74 patients did not ( group 2). • Most of diabetics, hypertensive men, and smokers came in the non-responder group. • The difference in age and duration of ED was significant between the Good and poor responders (pO.QOl).