Search In this Thesis
   Search In this Thesis  
العنوان
Effect of remifentanil versus esmolol on heart rate and arterial blood pressure during endotracheal intubation /
الناشر
Ahmed Abd El-Aleem Hosny,
المؤلف
Hosny, Ahmed Abd El-Aleem.
هيئة الاعداد
باحث / احمد عبدالعليم حسنى
مشرف / محمد نبيل سراج الدين
مشرف / مدحت عبدالفتاح عبدالله
مشرف / مدحت عبدالفتاح عبدالله
الموضوع
Intubation, Intratracheal-- Effect.
تاريخ النشر
2001.
عدد الصفحات
80 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
التخدير و علاج الألم
تاريخ الإجازة
1/1/2011
مكان الإجازة
جامعة المنصورة - كلية الطب - التخدير والعناية المركزة
الفهرس
Only 14 pages are availabe for public view

from 94

from 94

Abstract

Thirty six patients of either sex were the subjects of this study. Their age ranged from 20-40 years.
They were classified into three equal groups each was comprised of twelve patients. The patients of group I was given remifentanil in a dose of 1 μg/kg iv, while group II was given esmolol in a dose of 150 mg iv bolus dose, and group III was given 5ml saline prior to induction of anesthesia. In all patients, anesthesia was induced by propofol (2-2.5 mg/kg) followed by succinylcholine (1 mg/kg) to facilitate endotracheal intubation. Anesthesia was maintained with O2 : N2O in ratio of 1 : 2, halothane 0.5-0.75%. Muscle relaxation was achieved by an initial dose of atracurium 0.5mg/kg with top up doses of atracurium when needed. The assessment parameters were taken (SBP, DBP, MBP and HR) basal just before study drug, 1 minute after the study drug and1, 3 and 5 minutes after laryngoscopy and intubation.
The present study demonstrated that remifentanil 1 μg/kg iv or esmolol 150 mg iv bolus [about 2 mg/kg], 1 minute before induction of anesthesia are equipotent in blunting increase in heart rate and arterial blood pressure after laryngoscopy and tracheal intubation. Furthermore, remifentanil presented a better hemodynamic stability than esmolol following laryngoscopy and tracheal intubation.